Enzymic mechanisms involving concomitant transfer and hydrolysis reactions
نویسندگان
چکیده
منابع مشابه
Enzymic mechanisms involving concomitant transfer and hydrolysis reactions.
The kinetic parameters of ten different enzymic mechanisms in which bimolecular transfer reactions occur concomitantly with the hydrolysis of the donor molecule have been studied. The usefulness of these parameters for making a choice of mechanism is discussed. The analysis has been extended to the use of alternative substrates in bimolecular transfer reactions that proceed without the hydrolys...
متن کاملEnzymatic transfer and hydrolysis involving glutamine and asparagine.
The occurrence in bacteria of transferases, enzymes which catalyze the exchange of the p-aspartyl group of asparagine and the r-glutamyl group of glutamine with hydroxylamine or labeled ammonia, has been described (14). Transferase activities have also been found in extracts of mammalian tissues (5), in the mold Neurospora crassa,l and in extracts of green plants (6-8). Whereas transferase acti...
متن کاملThe enzymic hydrolysis of carrageenin.
Carrageenin is the water soluble polysaccharide extractable from the red algae Chondrus crispus and Gigartina stellata. The polysaccharide is essentially a polymer of alpha-D-galactopyranoside-4-sulphate. Smith et al. (1954) fractionated carrageenin with potassium chloride into two components and obtained a precipitable component which could form gels and a nongelling component which remained i...
متن کاملSimulations of enzymic reactions.
A fundamental problem in biology is the explanation of enzyme activity at the molecular level. The detailed origin of the rate acceleration of chemical reactions by enzymes is not fully understood, in spite of the immense amount of experimental work that has been done in this area [1,2]. T o describe an enzyme-catalysed reaction, its mechanism must be firmly established and intermediates must b...
متن کاملMechanisms and consequences of oxygen transfer reactions*
The geometry about oxygen in the transition-state structures for oxygen transfers from a nitrone to phosphorous, from a percarboxylic acid to a carbon–carbon double bond, and from an N-sulfonyl oxaziridine to a carbon–carbon double bond have been evaluated by the endocyclic restriction test. The former can proceed at an oblique angle, while the latter two require a large angle between the enter...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1973
ISSN: 0264-6021
DOI: 10.1042/bj1350469